RF15 | PMON293 Metabolic activation of tachysterol to biologically active hydroxyderivatives that act on VDR, AhR, LXRs and PPARγ receptors

Absorption of ultraviolet B (UVB) radiation by the B ring of 7-dehydrocholesterol (7-DHC) leads to the transformation of 7-DHC to previtamin D(3), which after absorption of additional UVB isomerizes to tachysterol(3) (T(3)) and lumisterol3 (L(3)). Previously we demonstrated that CYP11A1 can hydroxyl...

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Detalles Bibliográficos
Autores principales: Slominski, Andrzej, Kim, Tae-Kang, Slominski, Radomir, Song, Yuwei, Janjetovic, Zorica, Podgorska, Ewa, Reddy, Sivani, Song, Yuhua, Raman, Chander, Tang, Edith, Fabisiak, Adrian, Brzeminski, Pawel, Sicinski, Rafal, Atigadda, Venkatram, Jetten, Anton, Holick, Michael, Tuckey, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Steroid Hormones and Receptors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625629/
http://dx.doi.org/10.1210/jendso/bvac150.1515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625629/
http://dx.doi.org/10.1210/jendso/bvac150.1515

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