RF10 | PMON249 MicroRNA-21 Ablation Exacerbates Androgen-Mediated White Adipose Tissue Dysfunction and Impaired Insulin Signaling in a Mouse Model of Polycystic Ovary Syndrome

BACKGROUND: Polycystic ovary syndrome (PCOS) is characterized by oligo- or anovulation, polycystic ovaries, and hyperandrogenism. PCOS is associated with white adipose tissue (WAT) expansion and dysfunction, which has been linked to impaired insulin signaling in a number of metabolic diseases. Micro...

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Detalles Bibliográficos
Autores principales: Rezq, Samar, Basnet, Jelina, Huffman, Alexandra M, Yanes Cardozo, Licy L, Romero, Damian G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Reproductive Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625656/
http://dx.doi.org/10.1210/jendso/bvac150.1471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625656/
http://dx.doi.org/10.1210/jendso/bvac150.1471

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