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ODP405 Effects of Gonadotrope-Specific Knockout of Creb on HPG Axis Function in Mice
BACKGROUND AND OBJECTIVE: Reproduction is regulated by FSH and LH, which are synthesized and secreted by pituitary gonadotropes in response to pulsatile hypothalamic GnRH in a frequency dependent manner. Low and high GnRH pulse frequencies preferentially increase Fshb and Lhb expression, respectivel...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625677/ http://dx.doi.org/10.1210/jendso/bvac150.1361 |