Cargando…

ODP405 Effects of Gonadotrope-Specific Knockout of Creb on HPG Axis Function in Mice

BACKGROUND AND OBJECTIVE: Reproduction is regulated by FSH and LH, which are synthesized and secreted by pituitary gonadotropes in response to pulsatile hypothalamic GnRH in a frequency dependent manner. Low and high GnRH pulse frequencies preferentially increase Fshb and Lhb expression, respectivel...

Descripción completa

Detalles Bibliográficos
Autores principales: Hausken, Krist, Quinn, Alyssa, Kim, Han, Boehm, Ulrich, Carroll, Rona, Kaiser, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625677/
http://dx.doi.org/10.1210/jendso/bvac150.1361