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RF10 | PMON216 Aromatase Inhibition Fails to Exaggerate Weight Gain and Induce Bone Loss in Ovariectomized Female Marmosets

Declining serum estradiol (E2) levels during the menopausal transition are associated with increased central adiposity and heightened risk for metabolic disease. Ovarian estradiol, E2, supports female metabolic function. While ovariectomy (OVX) in rodents enables obesity, OVX in nonhuman primates (N...

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Detalles Bibliográficos
Autores principales: Willging, Molly, Kraynak, Marissa, Kuehlmann, Alex, Kapoor, Amita, Flowers, Matthew, Colman, Ricki, Levine, Jon, Abbott, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625735/
http://dx.doi.org/10.1210/jendso/bvac150.1465