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OR26-4 Glucocorticoid Receptor Expression and Signaling During Critical Illness, in Relation to the Duration of Illness and the Systemic Glucocorticoid Availability: A Prospective, Observational, Cross-Sectional Human and a Translational Mouse Study

Critically ill patients are thought to develop maladaptive glucocorticoid-resistance which convinces many clinicians to administer stress doses of glucocorticoids to overcome this state of glucocorticoid-resistance. However, supportive data arises mainly from whole blood cells. It is currently not k...

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Detalles Bibliográficos
Autores principales: Téblick, Arno, Van Dyck, Lisa, Van Aerde, Nathalie, Vander Perre, Sarah, Pauwels, Lies, Derese, Inge, Debaveye, Yves, Wouters, Pieter J, Vanhorebeek, Ilse, Langouche, Lies, Van den Berghe, Greet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625771/
http://dx.doi.org/10.1210/jendso/bvac150.1497