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OR26-4 Glucocorticoid Receptor Expression and Signaling During Critical Illness, in Relation to the Duration of Illness and the Systemic Glucocorticoid Availability: A Prospective, Observational, Cross-Sectional Human and a Translational Mouse Study
Critically ill patients are thought to develop maladaptive glucocorticoid-resistance which convinces many clinicians to administer stress doses of glucocorticoids to overcome this state of glucocorticoid-resistance. However, supportive data arises mainly from whole blood cells. It is currently not k...
Autores principales: | Téblick, Arno, Van Dyck, Lisa, Van Aerde, Nathalie, Vander Perre, Sarah, Pauwels, Lies, Derese, Inge, Debaveye, Yves, Wouters, Pieter J, Vanhorebeek, Ilse, Langouche, Lies, Van den Berghe, Greet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625771/ http://dx.doi.org/10.1210/jendso/bvac150.1497 |
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