Downregulation of MCF2L Promoted the Ferroptosis of Hepatocellular Carcinoma Cells through PI3K/mTOR Pathway in a RhoA/Rac1 Dependent Manner

METHODS AND RESULTS: The levels of MCF2L were detected by PCR and western blotting assay. The effect of MCF2L on ferroptosis was confirmed by MTT, colony formation assay, Brdu, in vivo animal experiment, and the content of Iron, GSH, ROS, and MDA. The underlying mechanisms were explored by PCR, west...

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Detalles Bibliográficos
Autores principales: Huang, Si-cong, Chen, Yi-mei, Hu, Ying-yu, Shi, Yong-jie, Xiao, Qi-wen, Li, Zhe, Kang, Jia-le, Zhou, Qiang, Shen, Gang, Jia, Hong-yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626212/
https://www.ncbi.nlm.nih.gov/pubmed/36330204
http://dx.doi.org/10.1155/2022/6138941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626212/
https://www.ncbi.nlm.nih.gov/pubmed/36330204
http://dx.doi.org/10.1155/2022/6138941

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