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Beta-Hydroxybutyric Acid Inhibits Renal Tubular Reabsorption via the AKT/DAB2/Megalin Signalling Pathway

AIM: Patients with diabetic ketosis often exhibit albuminuria. We previously found that acute hyperglycaemia can cause nephrotoxic injury. Here, we explored whether an excessive ketone body level causes kidney injury and the potential underlying mechanism. METHODS: Fifty-six type 2 diabetes without...

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Detalles Bibliográficos
Autores principales: Zuo, Minxia, Meng, Cheng, Song, Qian, Gao, Zhongai, Cui, Xiao, Wang, Jingyu, Li, Yongmei, Li, Xiaochen, Shan, Chunyan, Yang, Juhong, Chang, Baocheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626228/
https://www.ncbi.nlm.nih.gov/pubmed/36330072
http://dx.doi.org/10.1155/2022/3411123