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The efficacy of Paxlovid against COVID-19 is the result of the tight molecular docking between M(pro) and antiviral drugs (nirmatrelvir and ritonavir)

PURPOSE: Currently, a number of medications for coronavirus disease 2019 (COVID-19) treatment are tested in clinical trials; however, credible clinical studies are becoming increasingly difficult to come by. Paxlovid is a ritonavir-boosted nirmatrelvir drug that the U.S. Food and Drug Administration...

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Detalles Bibliográficos
Autor principal: Dawood, Ali Adel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University of Bialystok. Published by Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626444/
https://www.ncbi.nlm.nih.gov/pubmed/36368287
http://dx.doi.org/10.1016/j.advms.2022.10.001