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Immune mobilising T cell receptors redirect polyclonal CD8(+) T cells in chronic HIV infection to form immunological synapses
T cell exhaustion develops in human immunodeficiency virus (HIV) infection due to chronic viral antigenic stimulation. This adaptive response primarily affects virus-specific CD8(+) T cells, which may remain dysfunctional despite viral load-reducing antiretroviral therapy; however, abnormalities may...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626491/ https://www.ncbi.nlm.nih.gov/pubmed/36319836 http://dx.doi.org/10.1038/s41598-022-23228-3 |