Cargando…

Development of machine learning models for the screening of potential HSP90 inhibitors

Heat shock protein 90 (Hsp90) is a molecular chaperone playing a significant role in the folding of client proteins. This cellular protein is linked to the progression of several cancer types, including breast cancer, lung cancer, and gastrointestinal stromal tumors. Several oncogenic kinases are Hs...

Descripción completa

Detalles Bibliográficos
Autores principales: Khan, Mohd Imran, Park, Taehwan, Imran, Mohammad Azhar, Gowda Saralamma, Venu Venkatarame, Lee, Duk Chul, Choi, Jaehyuk, Baig, Mohammad Hassan, Dong, Jae-June
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626531/
https://www.ncbi.nlm.nih.gov/pubmed/36339714
http://dx.doi.org/10.3389/fmolb.2022.967510