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Mitochondrial respiration during normothermic liver machine perfusion predicts clinical outcome

BACKGROUND: Reliable biomarkers for organ quality assessment during normothermic machine perfusion (NMP) are desired. ATP (adenosine triphosphate) production by oxidative phosphorylation plays a crucial role in the bioenergetic homeostasis of the liver. Thus, detailed analysis of the aerobic mitocho...

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Detalles Bibliográficos
Autores principales: Meszaros, Andras T., Hofmann, Julia, Buch, Madita L., Cardini, Benno, Dunzendorfer-Matt, Theresia, Nardin, Florian, Blumer, Michael J., Fodor, Margot, Hermann, Martin, Zelger, Bettina, Otarashvili, Giorgi, Schartner, Melanie, Weissenbacher, Annemarie, Oberhuber, Rupert, Resch, Thomas, Troppmair, Jakob, Öfner, Dietmar, Zoller, Heinz, Tilg, Herbert, Gnaiger, Erich, Hautz, Theresa, Schneeberger, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626552/
https://www.ncbi.nlm.nih.gov/pubmed/36374770
http://dx.doi.org/10.1016/j.ebiom.2022.104311