SOCS5 knockdown suppresses metastasis of hepatocellular carcinoma by ameliorating HIF-1α-dependent mitochondrial damage

The Pringle maneuver (PM) is widely used during hepatocellular carcinoma (HCC) resection. However, it inevitably leads to ischemia and hypoxia, which promotes tumor metastasis. In this study, immunohistochemical staining of specimens from 130 HCC patients revealed that long-time PM significantly aff...

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Detalles Bibliográficos
Autores principales: Luo, Dingan, Wang, Youpeng, Zhang, Mao, Li, Haoran, Zhao, Deze, Li, Hui, Chen, Xiaowu, Jin, Cheng, Han, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626553/
https://www.ncbi.nlm.nih.gov/pubmed/36319626
http://dx.doi.org/10.1038/s41419-022-05361-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626553/
https://www.ncbi.nlm.nih.gov/pubmed/36319626
http://dx.doi.org/10.1038/s41419-022-05361-z

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