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Blockade of the BLT1-LTB(4) axis does not affect mast cell migration towards advanced atherosclerotic lesions in LDLr(−/−) mice

Mast cells have been associated with the progression and destabilization of advanced atherosclerotic plaques. Reducing intraplaque mast cell accumulation upon atherosclerosis progression could be a potent therapeutic strategy to limit plaque destabilization. Leukotriene B(4) (LTB(4)) has been report...

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Detalles Bibliográficos
Autores principales: Depuydt, Marie A. C., Vlaswinkel, Femke D., Hemme, Esmeralda, Delfos, Lucie, Kleijn, Mireia N. A. Bernabé, van Santbrink, Peter J., Foks, Amanda C., Slütter, Bram, Kuiper, Johan, Bot, Ilze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626554/
https://www.ncbi.nlm.nih.gov/pubmed/36319730
http://dx.doi.org/10.1038/s41598-022-23162-4