DNA read count calibration for single-molecule, long-read sequencing

There are many applications in which quantitative information about DNA mixtures with different molecular lengths is important. Gene therapy vectors are much longer than can be sequenced individually via short-read NGS. However, vector preparations may contain smaller DNAs that behave differently du...

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Detalles Bibliográficos
Autores principales: Soares, Luis M. M., Hanscom, Terrence, Selby, Donald E., Adjei, Samuel, Wang, Wei, Przybylski, Dariusz, Thompson, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626564/
https://www.ncbi.nlm.nih.gov/pubmed/36319642
http://dx.doi.org/10.1038/s41598-022-21606-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626564/
https://www.ncbi.nlm.nih.gov/pubmed/36319642
http://dx.doi.org/10.1038/s41598-022-21606-5

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