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USF2-mediated upregulation of TXNRD1 contributes to hepatocellular carcinoma progression by activating Akt/mTOR signaling

Thioredoxin reductase 1 (TXNRD1) is one of the major redox regulators in mammalian cells, which has been reported to be involved in tumorigenesis. However, its roles and regulatory mechanism underlying the progression of HCC remains poorly understood. In this study, we demonstrated that TXNRD1 was s...

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Detalles Bibliográficos
Autores principales: Huang, Wen-ya, Liao, Zhi-bin, Zhang, Jia-cheng, Zhang, Xin, Zhang, Hong-wei, Liang, Hui-fang, Zhang, Zun-yi, Yang, Tao, Yu, Jia, Dong, Ke-shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626593/
https://www.ncbi.nlm.nih.gov/pubmed/36319631
http://dx.doi.org/10.1038/s41419-022-05363-x