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IL-1 β gene (+3954 C/T, exon 5, rs1143634) and NOS2 (exon 22) polymorphisms associate with early aseptic loosening of arthroplasties

Aseptic prosthetic loosening (APL) and prosthetic joint infections (PJI) are frequent complications of hip and knee implants. Polymorphisms of cytokines and nitric oxide (NO), key inflammatory molecules in APL and PJI pathogenesis, could explain individual susceptibility to these complications. Thre...

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Detalles Bibliográficos
Autores principales: López-Anglada, Esteban, Collazos, Julio, Montes, A. Hugo, Pérez-Is, Laura, Pérez-Hevia, Imanol, Jiménez-Tostado, Sergio, Suárez-Zarracina, Tomás, Alvarez, Victoria, Valle-Garay, Eulalia, Asensi, Víctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626623/
https://www.ncbi.nlm.nih.gov/pubmed/36319725
http://dx.doi.org/10.1038/s41598-022-22693-0