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Folic acid inhibits 5‐methyltetrahydrofolate transport across the blood–cerebrospinal fluid barrier: Clinical biochemical data from two cases

OBJECTIVE: The use of folic acid (FA) has been discouraged in cerebral folate deficiency (CFD) because, theoretically, it could inhibit the transport of 5‐methyltetrahydrofolic acid (5MTHF) across the blood–cerebrospinal fluid (CSF) barrier. We present the clinical biochemical data of two cases with...

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Detalles Bibliográficos
Autores principales: Akiyama, Tomoyuki, Kuki, Ichiro, Kim, Kiyohiro, Yamamoto, Naohiro, Yamada, Yumi, Igarashi, Kazuya, Ishihara, Tomohiko, Hatano, Yuya, Kobayashi, Katsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626660/
https://www.ncbi.nlm.nih.gov/pubmed/36341171
http://dx.doi.org/10.1002/jmd2.12321