Activity-based probes trap early active intermediates during metacaspase activation

Metacaspases are essential cysteine proteases present in plants, fungi, and protists that are regulated by calcium binding and proteolytic maturation through mechanisms not yet understood. Here, we developed and validated activity-based probes for the three main metacaspase types, and used them to s...

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Detalles Bibliográficos
Autores principales: Štrancar, Vida, van Midden, Katarina P., Krahn, Daniel, Morimoto, Kyoko, Novinec, Marko, Funk, Christiane, Stael, Simon, Schofield, Christopher J., Klemenčič, Marina, van der Hoorn, Renier A.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626678/
https://www.ncbi.nlm.nih.gov/pubmed/36339259
http://dx.doi.org/10.1016/j.isci.2022.105247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626678/
https://www.ncbi.nlm.nih.gov/pubmed/36339259
http://dx.doi.org/10.1016/j.isci.2022.105247

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