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Single-cell RNA-seq transcriptomic landscape of human and mouse islets and pathological alterations of diabetes

Single-cell RNA sequencing has paved the way for delineating the pancreatic islet cell atlas and identifying hallmarks of diabetes. However, pathological alterations of type 2 diabetes (T2D) remain unclear. We isolated pancreatic islets from control and T2D mice for single-cell RNA sequencing (scRNA...

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Detalles Bibliográficos
Autores principales: Chen, Kai, Zhang, Junqing, Huang, Youyuan, Tian, Xiaodong, Yang, Yinmo, Dong, Aimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626680/
https://www.ncbi.nlm.nih.gov/pubmed/36339258
http://dx.doi.org/10.1016/j.isci.2022.105366