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BAP1 in cancer: epigenetic stability and genome integrity

Mutations in BAP1 have been identified in a hereditary cancer predisposition syndrome and in sporadic tumours. Individuals carrying familiar BAP1 monoallelic mutations display hypersusceptibility to exposure-associated cancers, such as asbestos-driven mesothelioma, thus BAP1 status has been postulat...

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Detalles Bibliográficos
Autores principales: Caporali, Sabrina, Butera, Alessio, Amelio, Ivano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626716/
https://www.ncbi.nlm.nih.gov/pubmed/36318367
http://dx.doi.org/10.1007/s12672-022-00579-x