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A perspective on oligonucleotide therapy: Approaches to patient customization

It is estimated that the human genome encodes 15% of proteins that are considered to be disease-modifying. Only 2% of these proteins possess a druggable site that the approved clinical candidates target. Due to this disparity, there is an immense need to develop therapeutics that may better mitigate...

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Detalles Bibliográficos
Autores principales: Thakur, Shikha, Sinhari, Apurba, Jain, Priti, Jadhav, Hemant R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626821/
https://www.ncbi.nlm.nih.gov/pubmed/36339619
http://dx.doi.org/10.3389/fphar.2022.1006304