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SHERLOCK4HAT: A CRISPR-based tool kit for diagnosis of Human African Trypanosomiasis

BACKGROUND: To achieve elimination of Human African Trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense (gHAT), the development of highly sensitive diagnostics is needed. We have developed a CRISPR based diagnostic for HAT using SHERLOCK (Specific High-sensitivity Enzymatic Reporter unLOCKi...

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Detalles Bibliográficos
Autores principales: Sima, Núria, Dujeancourt-Henry, Annick, Perlaza, Blanca Liliana, Ungeheuer, Marie-Noelle, Rotureau, Brice, Glover, Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626900/
https://www.ncbi.nlm.nih.gov/pubmed/36374773
http://dx.doi.org/10.1016/j.ebiom.2022.104308