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SHERLOCK4HAT: A CRISPR-based tool kit for diagnosis of Human African Trypanosomiasis
BACKGROUND: To achieve elimination of Human African Trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense (gHAT), the development of highly sensitive diagnostics is needed. We have developed a CRISPR based diagnostic for HAT using SHERLOCK (Specific High-sensitivity Enzymatic Reporter unLOCKi...
Autores principales: | Sima, Núria, Dujeancourt-Henry, Annick, Perlaza, Blanca Liliana, Ungeheuer, Marie-Noelle, Rotureau, Brice, Glover, Lucy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626900/ https://www.ncbi.nlm.nih.gov/pubmed/36374773 http://dx.doi.org/10.1016/j.ebiom.2022.104308 |
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