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OR22-2 Ghrelin Receptor (GHSR1a) Functional Selectivity As A Novel Pharmacotherapeutic Strategy To Normalize Dysfunctional Metabolic Homeostasis
The growth hormone secretagogue receptor-1a (GHSR1a) is the cognate G protein-coupled receptor (GPCR) for the orexigenic agonist ghrelin and the anorexigenic antagonist liver-expressed antimicrobial peptide-2 (LEAP2). The ghrelinergic system is activated under conditions of caloric restriction and/o...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626952/ http://dx.doi.org/10.1210/jendso/bvac150.947 |