Evaluation of nanobody-based biologics targeting purinergic checkpoints in tumor models in vivo

Adenosine triphosphate (ATP) represents a danger signal that accumulates in injured tissues, in inflammatory sites, and in the tumor microenvironment. ATP promotes tumor growth but also anti-tumor immune responses notably via the P2X7 receptor. ATP can also be catabolized by CD39 and CD73 ecto-enzym...

Descripción completa

Detalles Bibliográficos
Autores principales: Demeules, Mélanie, Scarpitta, Allan, Hardet, Romain, Gondé, Henri, Abad, Catalina, Blandin, Marine, Menzel, Stephan, Duan, Yinghui, Rissiek, Björn, Magnus, Tim, Mann, Anna Marei, Koch-Nolte, Friedrich, Adriouch, Sahil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626963/
https://www.ncbi.nlm.nih.gov/pubmed/36341324
http://dx.doi.org/10.3389/fimmu.2022.1012534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626963/
https://www.ncbi.nlm.nih.gov/pubmed/36341324
http://dx.doi.org/10.3389/fimmu.2022.1012534

Ejemplares similares