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Evaluation of nanobody-based biologics targeting purinergic checkpoints in tumor models in vivo

Adenosine triphosphate (ATP) represents a danger signal that accumulates in injured tissues, in inflammatory sites, and in the tumor microenvironment. ATP promotes tumor growth but also anti-tumor immune responses notably via the P2X7 receptor. ATP can also be catabolized by CD39 and CD73 ecto-enzym...

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Detalles Bibliográficos
Autores principales:	Demeules, Mélanie, Scarpitta, Allan, Hardet, Romain, Gondé, Henri, Abad, Catalina, Blandin, Marine, Menzel, Stephan, Duan, Yinghui, Rissiek, Björn, Magnus, Tim, Mann, Anna Marei, Koch-Nolte, Friedrich, Adriouch, Sahil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626963/ https://www.ncbi.nlm.nih.gov/pubmed/36341324 http://dx.doi.org/10.3389/fimmu.2022.1012534

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