OR08-3 Untargeted Nuclear Receptor-Wide Screening reveals Novel Ligands From the Brain and Gut.

The 48-member family of human nuclear receptors (NRs) plays major roles in metabolic homeostasis, immunity, and inflammatory responses, largely under the control of small lipophilic molecule interactions. A critical barrier precluding major breakthroughs in the discovery of new metabolic ligands is...

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Detalles Bibliográficos
Autores principales: Campbell, Jhenielle, Cummins, Carolyn, Krause, Henry, Liu, Jiabao, Main, Sridhar, Malekoltojari, Ainaz, Navarre, William, Peng, Hui, Sahin, Cigdem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genetics & Development
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627018/
http://dx.doi.org/10.1210/jendso/bvac150.942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627018/
http://dx.doi.org/10.1210/jendso/bvac150.942

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