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Clonorchis sinensis infection induces hepatobiliary injury via disturbing sphingolipid metabolism and activating sphingosine 1-phosphate receptor 2

Clonorchis sinensis (C. sinensis) infection induces severe hepatobiliary injuries, which can cause inflammation, periductal fibrosis, and even cholangiocarcinoma. Sphingolipid metabolic pathways responsible for the generation of sphingosine-1-phosphate (S1P) and its receptor S1P receptors (S1PRs) ha...

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Detalles Bibliográficos
Autores principales: Liu, Ji-Xin, Liu, Man, Yu, Guo-Zhi, Zhao, Qian-Qian, Wang, Jian-Ling, Sun, Yan-Hong, Koda, Stephane, Zhang, Beibei, Yu, Qian, Yan, Chao, Tang, Ren-Xian, Jiang, Zhi-Hua, Zheng, Kui-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627039/
https://www.ncbi.nlm.nih.gov/pubmed/36339341
http://dx.doi.org/10.3389/fcimb.2022.1011378