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Indoleamine 2,3-dioxygenase mediates the therapeutic effects of adipose-derived stromal/stem cells in experimental periodontitis by modulating macrophages through the kynurenine-AhR-NRF2 pathway

OBJECTIVES: Mesenchymal stromal/stem cell (MSC)-based therapy has become a promising approach to periodontal tissue repair. Adipose-derived stromal/stem cells (ASCs), compared with other dental or non-dental MSCs, serve as promising candidates for MSC therapy due to non-invasive acquisition and abun...

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Detalles Bibliográficos
Autores principales: Li, Hanyue, Yuan, Yu, Chen, Hongying, Dai, Hongwei, Li, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627099/
https://www.ncbi.nlm.nih.gov/pubmed/36270612
http://dx.doi.org/10.1016/j.molmet.2022.101617