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Lactate drives cellular DNA repair capacity: Role of lactate and related short-chain fatty acids in cervical cancer chemoresistance and viral infection

The characteristic feature of a cancer microenvironment is the presence of a highly elevated concentration of L-lactate in the tumor niche. The lactate-rich environment is also maintained by commensal mucosal microbiota, which has immense potential for affecting cancer cells through its receptoric a...

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Detalles Bibliográficos
Autores principales: Ciszewski, Wojciech M., Sobierajska, Katarzyna, Stasiak, Anna, Wagner, Waldemar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627168/
https://www.ncbi.nlm.nih.gov/pubmed/36340042
http://dx.doi.org/10.3389/fcell.2022.1012254