OR11-2 RNA Sequencing Reveals Unique Transcriptomic Signatures of the Thyroid in a Murine Lung Cancer Model Treated with PD-1 and PD-L1 Antibodies

Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, however, are associated with immune-related adverse events (irAEs). Thyroid dysfunction is among the most common irAEs, yet its mechanism has not been fully elucidated. To further explore the molecular mechanism of ICI-induced th...

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Detalles Bibliográficos
Autores principales: Dresner-Pollak, Rivka, Fridlender, Zvi G, Gurt, Irina, Kaisar-Iluz, Naomi, Lishinsky, Natan, Pollack, Rena, Shaul, Merav E, Stokar, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Thyroid
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627179/
http://dx.doi.org/10.1210/jendso/bvac150.1652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627179/
http://dx.doi.org/10.1210/jendso/bvac150.1652

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