ODP438 Canonical and Non-canonical Function of EZH2 in Progesterone Receptor Target Genes in Breast Cancer

Enhancer of Zeste homolog 2 (EZH2) is a histone methyltransferase which catalyzes the trimethylation of lysine 27 of histone H3 (H3K27me3), an epigenetic mark associated with chromatin compaction and transcriptional repression of target genes. This constitutes its canonical mechanism of action. Seve...

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Detalles Bibliográficos
Autores principales: Elizalde, Patricia, Belmonte, Martina, Cenciarini, Mauro, Deamicis, Agustina Roldan, Madera, Santiago, Mercogliano, Florencia, Mauro, Florencia, Bruni, Sofia, Russo, Rosalía Cordo, Schillaci, Roxana, Proietti, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Steroid Hormones and Receptors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627269/
http://dx.doi.org/10.1210/jendso/bvac150.1481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627269/
http://dx.doi.org/10.1210/jendso/bvac150.1481

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