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Enhancement of astrocytic gap junctions Connexin43 coupling can improve long‐term isoflurane anesthesia–mediated brain network abnormalities and cognitive impairment

AIM: Astrocytes are connected by gap junctions Connexin43 (GJs‐Cx43) forming an extensive intercellular network and maintain brain homeostasis. Perioperative neurocognitive disorder (PND) occurs frequently after anesthesia/surgery and worsens patient outcome, but the neural circuit mechanisms remain...

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Detalles Bibliográficos
Autores principales: Dong, Rui, Lv, Pin, Han, Yuqiang, Jiang, Linhao, Wang, Zimo, Peng, Liangyu, Ma, Zhengliang, Xia, Tianjiao, Zhang, Bing, Gu, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627365/
https://www.ncbi.nlm.nih.gov/pubmed/36153812
http://dx.doi.org/10.1111/cns.13974