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Enhancement of astrocytic gap junctions Connexin43 coupling can improve long‐term isoflurane anesthesia–mediated brain network abnormalities and cognitive impairment
AIM: Astrocytes are connected by gap junctions Connexin43 (GJs‐Cx43) forming an extensive intercellular network and maintain brain homeostasis. Perioperative neurocognitive disorder (PND) occurs frequently after anesthesia/surgery and worsens patient outcome, but the neural circuit mechanisms remain...
Autores principales: | Dong, Rui, Lv, Pin, Han, Yuqiang, Jiang, Linhao, Wang, Zimo, Peng, Liangyu, Ma, Zhengliang, Xia, Tianjiao, Zhang, Bing, Gu, Xiaoping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627365/ https://www.ncbi.nlm.nih.gov/pubmed/36153812 http://dx.doi.org/10.1111/cns.13974 |
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