Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggregation

INTRODUCTION: Neurofibrillary tangle (NFT) of hyperphosphorylated tau is a hallmark of Alzheimer's disease (AD) and related tauopathies. Tau lesion starts in the trans‐entorhinal cortex, from where it spreads to limbic regions, followed by neocortical areas. The regional distribution of NFTs as...

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Detalles Bibliográficos
Autores principales: Li, Longfei, Miao, Jin, Chu, Dandan, Jin, Nana, Tung, Yunn Chyn, Dai, Chun‐Ling, Hu, Wen, Gong, Cheng‐Xin, Iqbal, Khalid, Liu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627375/
https://www.ncbi.nlm.nih.gov/pubmed/36114722
http://dx.doi.org/10.1111/cns.13970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627375/
https://www.ncbi.nlm.nih.gov/pubmed/36114722
http://dx.doi.org/10.1111/cns.13970

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