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Sam50 exerts neuroprotection by maintaining the mitochondrial structure during experimental cerebral ischemia/reperfusion injury in rats

AIM: To investigate the role of Sam50, a barrel protein on the surface of the mitochondrial outer membrane, in cerebral ischemia–reperfusion (I/R) injury and its underlying mechanisms. METHODS: A middle cerebral artery occlusion/reperfusion (MCAO/R) model in adult male Sprague–Dawley rats was establ...

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Detalles Bibliográficos
Autores principales: Yin, Xulong, Wang, Jiahe, Yang, Siyuan, Li, Haiying, Shen, Haitao, Wang, Hui, Li, Xiang, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627377/
https://www.ncbi.nlm.nih.gov/pubmed/36074556
http://dx.doi.org/10.1111/cns.13967