5‐Fluorouracil reduces the fibrotic scar via inhibiting matrix metalloproteinase 9 and stabilizing microtubules after spinal cord injury

AIMS: Fibrotic scars composed of a dense extracellular matrix are the major obstacles for axonal regeneration. Previous studies have reported that antitumor drugs promote neurofunctional recovery. METHODS: We investigated the effects of 5‐fluorouracil (5‐FU), a classical antitumor drug with a high t...

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Detalles Bibliográficos
Autores principales: Xu, Yang, He, Xiuying, Wang, Yangyang, Jian, Jiao, Peng, Xia, Zhou, Lie, Kang, Yi, Wang, Tinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627390/
https://www.ncbi.nlm.nih.gov/pubmed/35918897
http://dx.doi.org/10.1111/cns.13930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627390/
https://www.ncbi.nlm.nih.gov/pubmed/35918897
http://dx.doi.org/10.1111/cns.13930

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