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ODP440 Characterization of the Major Single Nucleotide Polymorphic Variants of Aldo-Keto Reductase 1c3 (Type 5 17β-Hydroxysteroid Dehydrogenase)

BACKGROUND: Aldo-keto-reductase (AKR) 1C3, also known as type 517β-hydroxysteroid dehydrogenase and prostaglandin F synthase,is a member of the AKR superfamily that reduces aldehydes and ketones to primary and secondary alcohols. It plays an essential role in the peripheral formation of androgens an...

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Detalles Bibliográficos
Autores principales: Detlefsen, Andrea J, Wangtrakuldee, Beau, Penning, Trevor M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627392/
http://dx.doi.org/10.1210/jendso/bvac150.1482