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Ferroptosis contributes to hypoxic–ischemic brain injury in neonatal rats: Role of the SIRT1/Nrf2/GPx4 signaling pathway

AIMS: Hypoxic–ischemic brain injury (HIBI) often results in cognitive impairments. Herein, we investigated the roles of ferroptosis in HIBI and the underlying signaling pathways. METHODS: Ferrostatin‐1 (Fer‐1) or resveratrol (Res) treatments were administered intracerebroventricularly 30 min before...

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Detalles Bibliográficos
Autores principales: Li, Chang, Wu, Ziyi, Xue, Hang, Gao, Qiushi, Zhang, Yahan, Wang, Changming, Zhao, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627393/
https://www.ncbi.nlm.nih.gov/pubmed/36184790
http://dx.doi.org/10.1111/cns.13973