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Epitope-tagged and phosphomimetic mouse models for investigating natriuretic peptide-stimulated receptor guanylyl cyclases

The natriuretic peptide receptors NPR1 and NPR2, also known as guanylyl cyclase A and guanylyl cyclase B, have critical functions in many signaling pathways, but much remains unknown about their localization and function in vivo. To facilitate studies of these proteins, we developed genetically modi...

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Detalles Bibliográficos
Autores principales: Egbert, Jeremy R., Uliasz, Tracy F., Lowther, Katie M., Kaback, Deborah, Wagner, Brandon M., Healy, Chastity L., O’Connell, Timothy D., Potter, Lincoln R., Jaffe, Laurinda A., Yee, Siu-Pok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627482/
https://www.ncbi.nlm.nih.gov/pubmed/36340689
http://dx.doi.org/10.3389/fnmol.2022.1007026