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Bn(2)DT3A, a Chelator for (68)Ga Positron Emission Tomography: Hydroxide Coordination Increases Biological Stability of [(68)Ga][Ga(Bn(2)DT3A)(OH)](−)

[Image: see text] The chelator Bn(2)DT3A was used to produce a novel (68)Ga complex for positron emission tomography (PET). Unusually, this system is stabilized by a coordinated hydroxide in aqueous solutions above pH 5, which confers sufficient stability for it to be used for PET. Bn(2)DT3A complex...

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Detalles Bibliográficos
Autores principales: Price, Thomas W., Renard, Isaline, Prior, Timothy J., Kubíček, Vojtěch, Benoit, David M., Archibald, Stephen J., Seymour, Anne-Marie, Hermann, Petr, Stasiuk, Graeme J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627565/
https://www.ncbi.nlm.nih.gov/pubmed/36251390
http://dx.doi.org/10.1021/acs.inorgchem.2c01992