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LBODP080 Mc3r Expression In Liver Tissue Is Partially Responsible For The Severity Of Murine MC3R Deficiency Associated Obesity

The Melanocortin 3 Receptor (MC3R) is highly expressed in the hypothalamus, where it regulates energy balance and pubertal development. Function-altering SNPs in MC3R have been found to be associated with greater adiposity in both children and adults. Global Mc3r knockout mice show a phenotype of in...

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Detalles Bibliográficos
Autores principales: Jain, Arad, Patel, Tushar P, Altman, Elizabeth K, Tugarinov, Nicol, Levi, Noah J, Elizondo, Diana M, Arner, Brooke E, Roberson, Robin B, Caron, Alexandre, Elmquist, Joel K, Yanovski, Jack A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627641/
http://dx.doi.org/10.1210/jendso/bvac150.1218