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LBODP080 Mc3r Expression In Liver Tissue Is Partially Responsible For The Severity Of Murine MC3R Deficiency Associated Obesity
The Melanocortin 3 Receptor (MC3R) is highly expressed in the hypothalamus, where it regulates energy balance and pubertal development. Function-altering SNPs in MC3R have been found to be associated with greater adiposity in both children and adults. Global Mc3r knockout mice show a phenotype of in...
Autores principales: | Jain, Arad, Patel, Tushar P, Altman, Elizabeth K, Tugarinov, Nicol, Levi, Noah J, Elizondo, Diana M, Arner, Brooke E, Roberson, Robin B, Caron, Alexandre, Elmquist, Joel K, Yanovski, Jack A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627641/ http://dx.doi.org/10.1210/jendso/bvac150.1218 |
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