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m6A is required for resolving progenitor identity during planarian stem cell differentiation
Regeneration and tissue homeostasis require accurate production of missing cell lineages. Cell production is driven by changes to gene expression, which is shaped by multiple layers of regulation. Here, we find that the ubiquitous mRNA base‐modification, m6A, is required for proper cell fate choice...
Autores principales: | Dagan, Yael, Yesharim, Yarden, Bonneau, Ashley R, Frankovits, Tamar, Schwartz, Schraga, Reddien, Peter W, Wurtzel, Omri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627665/ https://www.ncbi.nlm.nih.gov/pubmed/35971838 http://dx.doi.org/10.15252/embj.2021109895 |
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