A non‐canonical scaffold‐type E3 ligase complex mediates protein UFMylation

Protein UFMylation, i.e., post‐translational modification with ubiquitin‐fold modifier 1 (UFM1), is essential for cellular and endoplasmic reticulum homeostasis. Despite its biological importance, we have a poor understanding of how UFM1 is conjugated onto substrates. Here, we use a rebuilding appro...

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Detalles Bibliográficos
Autores principales: Peter, Joshua J, Magnussen, Helge M, DaRosa, Paul A, Millrine, David, Matthews, Stephen P, Lamoliatte, Frederic, Sundaramoorthy, Ramasubramanian, Kopito, Ron R, Kulathu, Yogesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627666/
https://www.ncbi.nlm.nih.gov/pubmed/36121123
http://dx.doi.org/10.15252/embj.2022111015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627666/
https://www.ncbi.nlm.nih.gov/pubmed/36121123
http://dx.doi.org/10.15252/embj.2022111015

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