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TSG101 associates with PARP1 and is essential for PARylation and DNA damage‐induced NF‐κB activation
In a genome‐wide screening for components of the dsDNA‐break‐induced IKK‐NF‐κB pathway, we identified scores of regulators, including tumor susceptibility gene TSG101. TSG101 is essential for DNA damage‐induced formation of cellular poly(ADP‐ribose) (PAR). TSG101 binds to PARP1 and is required for P...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627669/ https://www.ncbi.nlm.nih.gov/pubmed/36124865 http://dx.doi.org/10.15252/embj.2021110372 |