Methyltetrazine as a small live-cell compatible bioorthogonal handle for imaging enzyme activities in situ

Bioorthogonal chemistry combines well with activity-based protein profiling, as it allows for the introduction of detection tags without significantly influencing the physiochemical and biological functions of the probe. In this work, we introduced methyltetrazinylalanine (MeTz-Ala), a close mimic o...

Descripción completa

Detalles Bibliográficos
Autores principales: Torres-García, Diana, van de Plassche, Merel A. T., van Boven, Emma, van Leeuwen, Tyrza, Groenewold, Mirjam G. J., Sarris, Alexi J. C., Klein, Luuk, Overkleeft, Herman S., van Kasteren, Sander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627743/
https://www.ncbi.nlm.nih.gov/pubmed/36349224
http://dx.doi.org/10.1039/d2cb00120a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627743/
https://www.ncbi.nlm.nih.gov/pubmed/36349224
http://dx.doi.org/10.1039/d2cb00120a

Ejemplares similares