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Methyltetrazine as a small live-cell compatible bioorthogonal handle for imaging enzyme activities in situ

Bioorthogonal chemistry combines well with activity-based protein profiling, as it allows for the introduction of detection tags without significantly influencing the physiochemical and biological functions of the probe. In this work, we introduced methyltetrazinylalanine (MeTz-Ala), a close mimic o...

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Detalles Bibliográficos
Autores principales:	Torres-García, Diana, van de Plassche, Merel A. T., van Boven, Emma, van Leeuwen, Tyrza, Groenewold, Mirjam G. J., Sarris, Alexi J. C., Klein, Luuk, Overkleeft, Herman S., van Kasteren, Sander I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	RSC 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627743/ https://www.ncbi.nlm.nih.gov/pubmed/36349224 http://dx.doi.org/10.1039/d2cb00120a

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