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RF03 | PMON288 Determining Mechanisms of Farnesoid×Receptor Regulation of Heme Biosynthesis and Ductular Reaction

Bile acids are increasingly becoming recognized as hormones, and their main endogenous receptor is the farnesoid X receptor (FXR). In order to investigate whether FXR is necessary to maintain proliferation of the bile ducts in response to injury, we challenged male and female wild-type (WT) and Fxr...

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Detalles Bibliográficos
Autores principales: Dean, Angela, Jungwirth, Emilian, Bailey, Keith, Panzitt, Katrin, Wagner, Martin, Anakk, Sayeepriyadarshini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627753/
http://dx.doi.org/10.1210/jendso/bvac150.1507